Psychometric validation of patient-reported outcome measures assessing chronic constipation

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Psychometric validation of patient-reported outcome measures assessing chronic constipation

BACKGROUND Measures assessing treatment outcomes in previous CC clinical trials have not met the requirements described in the US Food and Drug Administration's guidance on patient-reported outcomes. AIM Psychometric analyses using data from one Phase IIb study and two Phase III trials of linaclotide for the treatment of chronic constipation (CC) were conducted to document the measurement pro...

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ژورنال

عنوان ژورنال: Clinical and Experimental Gastroenterology

سال: 2014

ISSN: 1178-7023

DOI: 10.2147/ceg.s64713